Apertura 2021 Primera A
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Unión | 9 | 8 | 1 | 0 | 34 | 6 | 28 | 25 |
| 2 | Colón | 9 | 6 | 1 | 2 | 18 | 11 | 7 | 19 |
| 3 | El Quillá | 8 | 4 | 1 | 3 | 16 | 9 | 7 | 13 |
| 4 | La Salle | 8 | 4 | 1 | 3 | 14 | 13 | 1 | 13 |
| 5 | Peñarol | 8 | 3 | 2 | 3 | 10 | 9 | 1 | 11 |
| 6 | Independiente | 8 | 3 | 1 | 4 | 19 | 13 | 6 | 10 |
| 7 | Las Flores | 8 | 3 | 1 | 4 | 18 | 19 | -1 | 10 |
| 8 | Deportivo Santa Rosa | 9 | 2 | 2 | 5 | 7 | 25 | -18 | 8 |
| 9 | Santa Fe FC | 8 | 0 | 0 | 8 | 3 | 33 | -30 | 0 |
Apertura 2021 Primera B
| Pos | Club | P | W | D | L | F | A | GD | Pts |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Vecinal Gálvez | 10 | 8 | 1 | 1 | 36 | 8 | 28 | 25 |
| 2 | Pucará | 10 | 8 | 1 | 1 | 19 | 4 | 15 | 25 |
| 3 | Newells | 10 | 6 | 1 | 3 | 27 | 10 | 17 | 19 |
| 4 | El Cadi | 10 | 5 | 3 | 2 | 19 | 10 | 6 | 18 |
| 5 | Argentinos | 10 | 5 | 2 | 3 | 20 | 19 | +1 | 17 |
| 6 | San Cristóbal | 10 | 4 | 3 | 3 | 13 | 14 | 13 | 15 |
| 7 | La Perla del Oeste | 10 | 4 | 2 | 4 | 25 | 28 | -3 | 14 |
| 8 | Los Crack de Guadalupe | 10 | 3 | 3 | 4 | 9 | 12 | -3 | 12 |
| 9 | El Pozo | 10 | 2 | 1 | 7 | 7 | 19 | -12 | 7 |
| 10 | Nobleza | 10 | 1 | 1 | 8 | 5 | 24 | -19 | 4 |
| 11 | Atenas | 10 | 0 | 0 | 10 | 3 | 37 | -34 | 0 |